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Elena Povedano

Predoctoral Student, IEGD

Biologist and Geneticist

Degrees: Degree in Biology (University of Córdoba) and Master in Genetics and Evolution, biomedical specialty (University of Granada)

Positions during life: Collaborating student at the Genetics department, University of Córdoba; Master student at Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research (GENYO)

Honors and awards: FPI pre-doctoral Fellowship 2020 (training for researchers)

Recent Publications:

  • Castellini-Pérez O, Povedano-Espejo E, Barturen G, Martínez-Bueno M, Iakovliev A, Kerick M, López-Domínguez R, Marañón C, Martín J, Ballestar E, PRECISEADS Clinical Consortium, PRECISEADS Flow Cytometry Study Group, Borghi M, Qiu W, Zhu C, Shankara S, Spiliopoulou A, de Rinaldis E, Carnero-Montoro E, Alarcón-Riquelme ME. The Lupus Epigenome Relates to Genetics, Transcription and Serological Profiles with Dependency on Molecular Subtypes and Informs Drug Discovery. (preprint) medRxiv 2023.01.19.22283772. DOWNLOAD 
  • Teruel M., Barturen G., Martínez-Bueno M., Castellini-Pérez O., Barroso-Gil M., Povedano E., Kerick M., Català-Moll F., Makowska Z., Buttgereit A. PRECISESADS Clinical Consortium; PRECISESADS Flow Cytometry Study Group, Pers JO, Marañón C, Ballestar E, Martin J, Carnero- Montoro E, Alarcón-Riquelme ME. Integrative epigenomics in Sjögren´s syndrome reveals novel pathways and a strong interaction between the HLA, autoantibodies and the interferon signature. Sci Rep. 2021 Dec 2;11(1):23292. DOWNLOAD 
  • Carnero-Montoro, E., Barturen, G., Povedano, E., Kerick, M., Martinez-Bueno, M., PRECISESADS Clinical Consortium, Ballestar, E., Martin, J., Teruel, M., & Alarcón-Riquelme, M. E. Epigenome-Wide Comparative Study Reveals Key Differences Between Mixed Connective Tissue Disease and Related Systemic Autoimmune Diseases. Frontiers in Immunology, 2019, 10, 1880. DOWNLOAD

Summary of the investigation:

My previous research focuses on the integrated genomic and epigenomic study of a rare autoimmune disease (Mixed connective tissue disease), the search for genomic and epigenomic biomarkers for the disease and the mediating role of DNA methylation in it.

My tasks consist in giving support to ECHO research by formulation of hypotheses to test the mechanisms of DOHaD, and in the near future the analysis of genomic and epigenomic data.